SIMULATION IN MEDICAL EDUCATION: FOCUS ON ANESTHESIOLOGY AND CRITICAL CARE MEDICINE



Phenotypic plasticity and evolution of thermal tolerance in bacteria from temperate and hot spring environments

Phenotypic plasticity allows individuals to respond to the selective forces of a new environment, followed by adaptive evolution.We do not know to what extent phenotypic plasticity allows thermal tolerance evolution in bacteria at the border of their physiological limits.We analyzed growth and reaction norms to temperature of strains of two bacteri

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Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computational genomic analysis

Abstract Background A major challenge Jodhpur Boots in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription factor.We present a method for target identification that combines experimental characterization of binding requirements with computational genomic

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